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Thursday, May 31, 2012

Overdosing on Paracetamol...


Millions risk overdosing on paracetamol by ignoring the recommended daily limit

  • Nearly a quarter of adults taking paracetamol exceed  recommended limit within a 24-hour period
  • This can lead to an overdose and acute liver damage
  • Some ignore the manufacturer's dosage instructions
  • Others, particularly the elderly, forget how many tablets they have taken
By Graham Smith
|

Millions of people are at risk of unintentionally overdosing on Britain's most popular painkiller, scientists have warned.

Nearly a quarter of adults taking paracetamol are misusing the drug by exceeding the recommended limit with a 24-hour period.

This can lead to accidental overdoses and acute liver damage, according to researchers at Northwestern University in Chicago, who have called for 'urgent attention' to address the problem.


Risk: Nearly a quarter of adults taking paracetamol are misusing the drug by exceeding the recommended limit with a 24-hour period
Risk: Nearly a quarter of adults taking paracetamol are misusing the drug by exceeding the recommended limit with a 24-hour period

Many users ignore the manufacturer's dosage instructions, while some, particularly the elderly, forget how many tablets they have taken.

Others fail to realise that they are taking various medications containing the active ingredient acetaminophen.

Doctors recommend a maximum daily dose of eight 500mg paracetamol tablets, to be taken no more than two at a time during each four-hour period.


 
One consequence of an overdose of acetaminophen causing liver failure is a potentially fatal build-up of fluid in the brain.

Lead researcher Dr Michael Wolf and his team looked at the prevalence and potential misuse of pain medication containing acetaminophen as well as the likelihood of overdosing.

They interviewed 500 adult patients receiving care at outpatient general medicine clinics in Atlanta, Georgia, and Chicago, Illinois, between September 2009 and March 2011.

Over half the patients reported some acetaminophen use and 19 per cent were 'heavy users', taking it every day, or at least a couple of times a week, during the previous six months.

Doctors recommend a maximum daily dose of eight 500mg paracetamol tablets, to be taken no more than two at a time during each four-hour period

The researchers tested whether these patients understood the recommended dosage and were able to self-administer over-the-counter acetaminophen appropriately.

They did this by testing if the patients could work out the proper dosing of a single pharmacy medication over a 24-hour period and then assessing the risk of their 'double-dipping', or simultaneously taking two acetaminophen-containing products, and thereby exceeding the recommended dose.

The scientists found that nearly a quarter of the participants were at risk of overdosing on pain medication using a single paracetamol product, by exceeding the 4g limit in a 24-hour period

Five per cent made serious errors by dosing out more than 6g. In addition, nearly half were at risk of overdosing by 'double-dipping' with two acetaminophen-containing products.

Dr Wolf said: 'Our findings suggest that many consumers do not recognise or differentiate the active ingredient in over-the-counter pain medicines, nor do they necessarily closely adhere to package or label instructions.

'Given the prevalence of the problem, risk of significant adverse effects, and lack of a learned intermediary - for instance, a physician to guide decision making and counsel consumers on proper use - we believe this to be a serious public health threat requiring urgent attention.'

The research is published online in the Journal of General Internal Medicine.

Tuesday, May 8, 2012

Good Info about your Ears...


Listen up! All the advice you ever need to hear about your ears

By John Graham



The ear is a complex organ and can be divided into three main regions
The ear is a complex organ and can be divided into three main regions

We know what our ears are for. But as a surgeon specialising in these delicate structures, I am all too aware that many people don't know how to look after them.

For instance, most of us think nothing of wiggling a cotton bud inside the ear trying to scoop out wax. It is considered part of daily hygiene by many  -  but in fact overzealous cleaning can often lead to infections and even permanent hearing damage. 

The ear is a complex organ and can be divided into three main regions. The outer ear protects the eardrum from direct damage and channels sound waves through the ear canal to the eardrum.

The middle ear, separated from the outer ear by the eardrum, is an air-filled cavity that connects to the back of the nose through the Eustachian tube, which opens when you swallow or yawn. Sound waves make the eardrum vibrate. 

Inside the middle ear cavity are tiny bones that transmit vibrations from the eardrum to the inner ear or cochlea. This consists of a fluid-filled tube, coiled like a snail shell, and contains the minuscule hair cells that translate sound waves into nerve impulses that travel up to the brain. 

The health of our ears is something we should be diligent about because  -  apart from keeping us free of pain and infection  -  it could save our hearing. 


Here are the questions I get asked by patients that should help keep them in good shape.

 

Q. Is there a safe way to clean wax from an ear?

Earwax, or cerumen, is an antibacterial substance produced by glands in the ear canal to prevent infection and help rid the ear of dead skin cells. It is easy and hygienic to clean the outer ear flap, or pinna, with soap and water. 

The skin of the ear canal is designed to help the wax move outwards, like a conveyor belt, taking the wax and any other debris with it. 

Cotton buds are a similar width to the ear canal and actually push wax further inside, although if you wish to use one to clean the edge of the ear canal  -  the visible part  -  that is fine. 
However, do this delicately as they can scrape the skin, leading to an infection, and even puncture the eardrum if pushed in too deeply. 

Some people use olive oil to soften wax and speed its exit, but it can block the ear further. Hopi ear candles claim to suck wax out of the ear by producing a vacuum from a burning hollow candle. These have failed tests for safety and efficacy, and the Food and Drug Administration in the US has banned them for sale as a health remedy. 

If you feel that your ear needs unblocking, visit a doctor. Using special instruments to look inside the ear, they can confirm whether there is a blockage and what is causing it.

Q. What should my earwax look like?

Some people have soft, orange wax while others have drier, brown wax. As long as there's no thick, green discharge  -  which is usually pus emanating from an ear infection  -  don't worry about any changes in colour or consistency.

Q. Why are my ears itchy and flaky?

This is usually a sign of eczema or psoriasis. Your doctor should be able to recommend a steroid ointment that will help control the condition and stop the itch, so you don't damage the ear canal by scratching.
If there is any long-term problems with your ears, your GP should refer you to a specialist. In most cases, the cause of pain is not sinister
If there is any long-term problems with your ears, your GP should refer you to a specialist. In most cases, the cause of pain is not sinister

Q. How do I treat an infection?

There are two main types of ear infection and both need treatment from a doctor. External ear infections usually occur after exposure to dirty water. They are more common in people who suffer from eczema in the ear canal and can recur if the skin doesn't have time to heal properly. 

The ear becomes painful, swells and is blocked with pus. This is usually caused by bacteria but can also be down to a fungal infection. It is treated by mopping the pus and putting antibiotic ear drops into the canal. 

Acute middle-ear infections often follow colds. The ear becomes blocked by fluid in the middle ear. This can sometimes make the eardrum rupture. Usually the infection is viral, but bacteria can also invade the middle ear. Bacterial infections may need oral antibiotics. 

A spot or boil in the ear canal can also be painful and will normally need antibacterial drops.

Q. My doctor says I don't have an infection yet I am still in pain

Your GP should refer you to a specialist if there is any long-term problem with your ears. 

In most cases, the cause of pain is not sinister  -  the ear shares the same nerves as nearby body parts so sometimes a throat infection or even a problem with the joints in the neck will manifest itself as ear pain. 

Cancers of the throat, tongue and tonsils can cause ear pain too, but these are rare.

Q. Why has my hearing deteriorated?

If the hearing loss is sudden, it is a medical emergency. Visit your GP immediately and if he or she cannot see a problem, ask to be referred, as the deafness could be in the inner ear, with damage to the hair cells. It may be possible to rectify sudden inner-ear hearing loss caught within the first week or two. 

A slow loss of hearing is usually associated with old age, but if only one ear is affected, or if there is a significant difference between the loss in the two ears, visit a specialist.
Some medications can cause deafness, although this is rare.

Q. Will loud music damage my ears in the long term?

Yes. Listening to loud music for a prolonged period overstimulates and can eventually kill the hair cells in the inner ear. The human ear is not designed to hear noises above 85dB (decibels), yet the average rock concert is 120dB. 

The ringing in your ear after listening to loud music is called tinnitus and is a symptom of over-stimulation. Everyday sounds can cause irreversible damage too. 

If you are walking along a street undergoing roadworks, cross the road. While the men using a pneumatic drill will wear ear-protectors, you will have nothing.

People who use earphones should buy special inserts that cut background noise and avoid the need to turn up the volume further.

Q. What else might damage the ears?

A slap on the ear can happen in contact sports and can trigger a perforated eardrum, which is very painful. In most cases the membrane will heal by itself in about six weeks, but the ear must be kept dry at all times, otherwise an infection can develop. 

Being hit in the ear while swimming is more likely to cause damage as the water forced into the ear puts the eardrum under a lot of pressure and is more likely to burst it.
Skull trauma and fractures will often also damage the inner ear.

Q. Can I ease the pain when flying?

Yes. Cabins are pressurised but will not be able to mimic ground-level pressure perfectly, so the change in altitude causes the pressure in the outer ear to be higher than that of the middle ear, leading the eardrum to bulge inwards. 

To compensate for this, the Eustachian tube should briefly open to allow a small amount of air into the middle ear and so normalise the ear pressure. This will eventually happen naturally but you can force it by holding your nose closed and blowing gently. Yawning helps too, but you can't make this happen. 

To help your ears adjust naturally, I recommend using a couple of puffs of a decongestant nasal spray an hour before flying or landing.

Saturday, May 5, 2012

Gentle Jogging could prolong your life...


Gentle jogging once a week 'can add six years to your life'

By Daily Mail Reporter
|
Get those feet moving: Jogging for an hour a week from the age of 20 to 70 takes 108 days but adds more than five years to your life
Get those feet moving: Jogging for an hour a week from the age of 20 to 70 takes 108 days but adds more than five years to your life

Jogging for just an hour a week can increase your life expectancy by around six years, reveal scientists.
Even better news is that a gentle jog is better for you than any sort of extreme workout, the study concludes.

Researchers found that jogging at a slow or average pace for one or two hours per week can increase the life expectancy of men by 6.2 years and women by 5.6 years, reducing the risk of death by 44 per cent.

The results challenge previous studies into jogging which questioned whether it is healthy or hazardous, with the debate kicking off in the 70s when middle aged men began taking an interest in the exercise.

However, following the death of a few men who died while out on a run, the media suggested jogging might be too strenuous for middle aged people, casting doubts over the past-time.

As part of the Copenhagen City Heart study, a cardiovascular study of around 20,000 men and women aged 20 to 93, researchers set about quashing previous suggestions that jogging is bad for people’s health.

The study has so far resulted in over 750 papers, and has previously explored associations for longevity with different forms of exercise and other factors.

 
Researchers believe jogging delivers multiple health benefits, improving oxygen uptake, lowering blood pressure, preventing obesity, improving cardiac function and improving psychological function, as well as many more benefits.

Dr Peter Schnohr, from the Bispebjerg University Hospital, said: 'The improved psychological wellbeing may be down to fact that people have more social interactions when they’re out jogging.'

Read more: http://www.dailymail.co.uk/health/article-2138869/Jogging-increases-life-expectancy-Gentle-jogging-week-add-6-years-life.html#ixzz1u0ftgbO5

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